- ADC Cytotoxic Payloads / Warheads market is anticipated to grow at a CAGR of 12.4% till 2030
- With six approved drugs, namely POLIVY™, LUMOXITI™, BESPONSA®, MYLOTARG™, KADCYLA®, ADCETRIS® and over 300 drugs underdevelopment, antibody drug conjugates (ADCs) have emerged as a promising class of targeted therapies for various disease indications
- Roots Analysis has announced the addition of “ADC Cytotoxic Payloads / Warheads: Products and Services Market, 2021-2030” report to its list of offerings.
- Given the fact that ADCs are highly potent cytotoxic molecules, the manufacturing of ADCs requires elaborate and advanced technical capabilities and highly potent chemical substances. Specifically, the multi-step process of production of cytotoxic payloads, which are complex structures used in ADCs, requires a specially designed and contained environment, dedicated manufacturing facilities, specialized analytical and purification techniques, and storage facilities.
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- Key Market Insights
- Over 40 companies claim to offer ADC cytotoxic payloads / warheads for ADCs
- Presently, the market is dominated by the presence of large (501-10,000 employees) and mid-sized companies ( 51-500 employees). It is worth noting that majority (44%) of the firms engaged in this domain are based in Europe, followed by North America (28%) and Asia Pacific (28%).
- More than 430 patents related to ADC cytotoxic payloads / warheads have been granted / filed between 2016-2021
- A significant increase has been observed in the number of patent applications filed over the last few years. Majority (80%) of the patents were filed / granted in North America; other key regions with significant intellectual capital include regions of Europe and South Korea
- Close to 40 partnerships have been inked among various industry and non-industry players between 2016 and 2021
- Maximum number of partnerships were established in 2021, indicating a recent rise in the interest of players engaged in this domain. It is worth highlighting that, majority of the deals were licensing agreements, representing over 35% of the total number of partnerships signed in the given time period.
- Close to USD 1,100 million has been invested by both private and public investors, since 2016
- Of the total amount invested, over USD 719 million was raised through venture capital financing, representing over 42% of the overall funding activity in this domain. Further, 5 instances of private placements were also reported, wherein players collectively raised more than USD 190 million.
- North America and Europe are anticipated to capture larger share of the market share by 2030
- Growth in this domain is anticipated to be primarily driven by the demand of auristatins and maytansinoids payloads. It is worth mentioning that ADC cytotoxic payloads / warheads market for microtubule inhibitors is likely to capture nearly 40% of the total market share by 2030.
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- Key Questions Answered
- • Who are the leading players engaged in the development of ADC cytotoxic payloads / warheads?
- • What kind of partnership models are commonly adopted by industry stakeholders engaged in the ADC cytotoxic payloads / warheads domain?
- • Which key investors are likely to drive the development efforts related to ADC cytotoxic payloads / warheads?
- • How has the intellectual property landscape of ADC cytotoxic payloads / warheads evolved over the years?
- • How is the current and future opportunity likely to be distributed across key market segments?
- The financial opportunity within the ADC cytotoxic payloads / warheads market has been analyzed across the following segments:
- Type of Payload
- • Microtubule Inhibitors
- • DNA Damaging Agents
- • Topoisomerase Inhibitors
- Payload
- • Auristatins
- • Camptothecin
- • Maytansinoids
- Type of Product
- • Commercialized Products
- • Clinical Products
- Key Geographical Regions
- • North America
- • Europe
- • Asia Pacific
- The report features inputs from eminent industry stakeholder(s), who were very optimistic concerning the growth of the ADC cytotoxic payloads / warheads market. It includes detailed transcripts of the discussions held with the senior representatives of the stakeholder firms.
- The report also includes detailed profiles of the companies (listed below) engaged in developing ADC cytotoxic payloads / warheads; each profile features an overview of the company, its financial information (if available), details on its product portfolio, recent developments, and an informed future outlook.
- • Abzena
- • Levana Biopharma
- • MabPlex
- • NJ Bio
- • Novasep
- • STA Pharmaceuticals
- • Synaffix
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